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Monday to Friday - 9.30 to 6.00 Saturday - 9.30 to 4.00
| Parameter | Specification (e.g., USP/EP) | Test Result | Method (e.g., USP, HPLC) |
|---|---|---|---|
| Assay (Purity) | 98.0% - 102.0% | 99.5% | Titration or HPLC |
| Appearance | White or almost white, crystalline powder | Complies | Visual |
| Identification | Positive (IR, UV, TLC) | Complies | Spectroscopic/Chromatographic |
| Water (Loss on Drying) | 5.0% | 1.2% | Karl Fischer Titration |
| Residue on Ignition | 0.1% | 0.05% | Gravimetric |
| Heavy Metals | 20 ppm | < 10 ppm | ICP-MS or Limit Test |
| Related Substances | Individual impurity 0.5% | Complies | HPLC |
| Specific Rotation | -8.0 to -10.0 | -9.2 | Polarimetry |
Packaging: 25 kg per fiber drum with double polyethylene liner."
Storage Conditions: Preserve in well-closed, light-resistant containers, in a cool, dry place."
Shelf Life/Expiry Date: Validity period under recommended storage
Vitamin B1's primary role is to act as a coenzyme (thiamine pyrophosphate) in converting carbohydrates from food into usable cellular energy (ATP). It is also essential for proper nervous system function and supports heart health.
Excellent sources include:
Whole Grains & Fortified Foods: Brown rice, oatmeal, fortified breakfast cereals, whole wheat bread.
Legumes: Black beans, lentils, soybeans.
Nuts & Seeds: Sunflower seeds, flaxseeds.
Animal Sources: Pork (especially lean cuts), trout, tuna.
Yeast: Nutritional yeast is a potent source.
Deficiency can lead to:
Early/Mild: Fatigue, irritability, reduced reflexes, muscle weakness.
Severe: Beriberi (with "wet" form affecting the heart and "dry" form affecting nerves) and Wernicke-Korsakoff syndrome (a serious brain disorder often linked to chronic alcoholism, causing confusion, vision issues, and memory loss).
Individuals with Alcohol Use Disorder: Alcohol severely impairs thiamine absorption and storage.
People with Certain Medical Conditions: Those with Crohn's disease, anorexia, or who have undergone bariatric surgery.
Older Adults: Due to potentially poor diet and decreased absorption.
People with Diets High in Refined Carbs/Sugar: These increase the body's demand for B1 for metabolism.
Vitamin B1 is considered very safe with a low risk of toxicity. It is water-soluble, so excess amounts are typically excreted in urine. There is no established Tolerable Upper Intake Level (UL) because no adverse effects from high oral intakes have been reliably reported. However, extremely high doses from supplements are unnecessary and not recommended.
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